4/9/11

Acute biphenotypic leukemia with philadelphia chromosome?


Acute biphenotypic leukemia with philadelphia chromosome?
My daughter has been diagnosed with Acute Biphenotypic Leukemia a couple of weeks ago. Today, the hematologists told us that she also has the philadelphia chromosome. So, they have suggested that as treatment we proceed with a bone marrow transplant as our final course of treatment. I have a couple of questions regarding this, the first being.... What are the chances that the leukemia will relapse after the bone marrow transplant? How much does having the Philadelphia chromosome change these odds? Where is the Philadelphia chromosome located? Is it in the bone marrow? Is it part of the genetic make-up of the body? I am not understanding how exactly this chromosome is changing the prognosis. I guess part of the issue is that this type of leukemia is extremely rare, especially when coupled with the Philadelphia chromosome and the answers to be found anywhere are few and far between. They also want to start giving her the drug Gleevec. I guess what I am looking for in the end is some type of hope with the survivability of her cancer. Is a cancer free life obtainable for her?

- SilenceIsDeafening
They would not be treating if a cancer free life was not attainable. Stay Positive!! Your daughter can tell if your negative about this or think shes not going to make it. Even if the percentage of survival is small, someone has to make up that percentage. Your daughter can be part of that percentage she can survive, attitude is everything. Because this cancer is so specific to your daughter you should really ask her oncologist these questions so you are getting correct information. Get a second or third opinion if you need to. Good Luck and Stay Strong
xxxx

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