4/13/11

are there really differences between Leukemia reactions & Leukemia diseases ?


are there really differences between Leukemia reactions & Leukemia diseases ?
i mean according to the Neutrophils` role in the blood as antibacterial & phagocyte in the immune system ,how can we distinguish one case from the other one?if it`s poosible,,,,,& thanks

- asian06guy
I'm sure you're aware that a leukemoid reaction, which is simply a physiological response secondary to stress/infection is not the same as leukemia, which is a primary blood malignancy. If you do a leukocyte alkaline phosphatase (LAP) stain, you'll find that the former is usually associated with a high LAP score, whereas the latter is low.

In a clinical setting, you could also be able to come to a diagnosis based on the context (e.g., if the patient has hemorrhage, infection, is on steroids, etc., it is likely that it is a leukemoid reaction).

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