4/7/11

Chromosomal translocations involving the MLL gene: Molecular mechanisms [An article from: DNA Repair]

Chromosomal translocations involving the MLL gene: Molecular mechanisms [An article from: DNA Repair]




This digital document is a journal article from DNA Repair, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
A wide array of recurrent, non-random chromosomal translocations are associated with hematologic malignancies; experimental models have clearly demonstrated that many of these translocations are causal events during malignant transformation. Translocations involving the MLL gene are among the most common of these non-random translocations. Leukemias with MLL translocations have been the topic of intense interest because of the unusual, biphenotypic immunophenotype of these l





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Chromosomal translocations involving the MLL gene: Molecular mechanisms [An article from: DNA Repair]



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