5/17/11

What happens if a person has leukemia and AIDS?


What happens if a person has leukemia and AIDS?
I know leukemia means the white cells are multiplying chaotically, and AIDS means the immunity is affected. How would these two diseases handle each other? What would possibly happen with a person having both?

- Cara
Take pills

- Gordon R
i read if someone with aids get swine flu it could make aids airborne

- ISOCERTIFIED
I think that death would be imminent

- Sophia
That's a double-whammy :/

- jc8391
Feline Leukemia and AIDS

Years ago, one of the Grouppe Kurosawa members had a scientific colleague named Diane. Diane was single, beautiful, smart and extremely personable. She also had a Ph.D from Harvard and did not suffer fools well. She scared men, to be honest. She didn't mean to…she was just smarter than they were and they knew it. At the age of 30, she found that the only stable, long term relationship she had was with her cat, Tigger. Tigger was a Moose cat…we are talking about a big tabby cat. If Tigger wanted to sit in your lap, it was not a topic of negotiation. Every morning Tigger would wake Diane by punching her in the nose. It was intended to be a "love tap", but it became increasingly more forceful if she did not immediately wake up. This was Tigger's way of telling Diane, "You have my permission to wake up and feed me…NOW." One day, Tigger stopped punching Diane in the morning. He was listless and not his usual self. Diane took him to the veterinarian who diagnosed Tigger as having feline leukemia. She was devastated. Boyfriends come and go (literally), but Tigger was always there to comfort her. Now, he was dying and she couldn't deal with it. So, being the intelligent woman that she was, she refused to give in. She devoured the scientific literature on feline leukemia, and talked to numerous experts across the nation. In the final analysis, all they could recommend was that she force-feed Tigger. Find something he likes and stuff it down his throat. If Tigger stops eating, he will lose the nutritional energy required to fight off the virus. Guess what? She stuffed him full of Chinese pot stickers every night. She put some medicine and supplements in the pot stickers and he ate them—not voluntarily—but he managed to choke them down. This feeding ritual went on for 4-6 weeks. Tigger seemed to be doing fine, but Diane couldn't really tell. Some days were better than others. One morning, Diane woke up to a sensation she hadn't felt in weeks. Tigger was once again punching her in the nose. He had beat the virus. Diane didn't go to the lab that day. She spent the entire day hugging her best friend. It was a good day.

This is the moral of our story. Nothing is absolute. Cats can live with the feline immunodeficiency virus (cat AIDS) their entire lives without getting sick. Cats can also beat an infection with feline leukemia if their owners do not allow them to stop eating. However, if a cat contracts both viruses, death is almost certain. This essay was written to help people understand the nature of these viruses and how to treat them, should that become necessary. There is always hope. Just ask Tigger.

The feline immunodeficiency virus (FIV) which causes AIDS in cats is very similar to human HIV. However, there are a number of differences. The FIV virus does not contain the VPR gene, and the presence of NEF, a gene which ostensibly plays an important role in the development of human AIDS (see HIV vaccine and AIDS essay), is suspected to be present in only a few FIV viral isolates. The lack of the VPR protein in FIV probably accounts for the mild nature of the disease compared to HIV. In FIV, the TAT protein is called ORF-A. Very little is known about the biological role it plays in the development of feline AIDS. The clinical syndrome of feline AIDS is very similar if not identical to that reported for human AIDS. One would be hard pressed to find an immune defect found in HIV+ individuals that was not also present in FIV infected cats. Since cats can be experimentally infected with FIV, a great deal is known about the early immune response to this virus. Pathogen-free cats are those bred and housed in a pathogen-free environment, and born by caesarian section. These cats are very resistant to feline AIDS when the FIV virus is introduced by injection. The cats become viremic (they have a substantial amount of virus in their body), but they do not develop AIDS. If the FIV infection is transmitted by natural infection, e.g. by housing the pathogen-free cats with normal, FIV-infected cats, the cats do develop AIDS. Normal cats harbor many diseases besides FIV. Feline leukemia virus (FeLV), in particular, is extremely common in house cats. Apparently, FeLV synergizes with FIV to cause AIDS. We believe we know why this occurs.

With respect to human AIDS, the question that begs asking is whether the human HIV virus, in the absence of opportunistic infections, or immunosuppressive stressors such as drug abuse, and surgery, can cause AIDS without help from outside factors? The HIV virus is more virulent (toxic) than the FIV virus, perhaps because it contains VPR and NEF gene sequences that FIV does not. Many natural FIV infections regress and the cats becoming seronegative over time (they no longer have anti-FIV antibodies in their blood). This rarely happens with HIV. In Africa, the average lifespan of someone infected with HIV is 3 years. In Western countries, it is 10 years. Why the

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