5/18/11

Anyone being treated for Chronic Myelomonocytic Leukemia (CMML)?


Anyone being treated for Chronic Myelomonocytic Leukemia (CMML)?
My husband was recently diagnosed with CMML, due to a bone marrow test.(he will be 74 in December). His white cell count was 16000th and went up to 18000th. last test was 16700th.He was told as the result of last test that was normal, but his primary Dr. was concerned when it elevated to 16000th's. What is a normal range?
He is being treated for low platelets. 1 - 1 1/2 years ago they showed up at about 45 (thousandths)...since then he has given up smoking & drinking and regular coffee. The platelet count (last tested)was about 65.
He has none of the symptoms related to CMML (weakness..shortness of breath..anemia..bleeding..bruising..recurrent infections..enlarged spleen)and his hematoligist doesn't seem to be to concerned about it. Saw him last month and he doesn't want to see him for another 3 months.
Hematoligist says platelets can be added to do this procedure,and would probably be an over night stay in the hospital.
Back to original question.What is normal range for White Blood Cells?

- medicgvd
The normal range varies slightly but is generally between 4,300 and 10,800 cells per cubic millimeter (cmm). This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 109 cells per liter.

- dark and beautiful
The defining features of CMML are an absolute monocytosis of >1X109/l, increased numbers of monocytes in bone marrow, and a variable degree of dyplasia in all three lineages. Myeloblasts and promonocytes comprise less than 5% of nucleated cells in peripheral blood and less than 20% of cells in bone marrow. Roughly half of patients present with an elevated white cell count that is commonly associated with hepatomegaly and splenomegaly, the so-called myeloproliferative form of the disease. Patients lacking these features are generally considered to have the myelodysplastic form of the disease

Here are a few normal values that you would be interested to learn about:
HEMATOCRIT (HCT)
Normal Adult Female Range: 37 - 47%
Optimal Adult Female Reading: 42%
Normal Adult Male Range 40 - 54%
Optimal Adult Male Reading: 47
Normal Newborn Range: 50 - 62%
Optimal Newborn Reading: 56



HEMOGLOBIN (HGB)
Normal Adult Female Range: 12 - 16 g/dl
Optimal Adult Female Reading: 14 g/dl
Normal Adult Male Range: 14 - 18 g/dl
Optimal Adult Male Reading: 16 g/dl
Normal Newborn Range: 14 - 20 g/dl
Optimal Newborn Reading: 17 g/dl



MCH (Mean Corpuscular Hemoglobin)
Normal Adult Range: 27 - 33 pg
Optimal Adult Reading: 30



MCV (Mean Corpuscular Volume)
Normal Adult Range: 80 - 100 fl
Optimal Adult Reading: 90
Higher ranges are found in newborns and infants



MCHC (Mean Corpuscular Hemoglobin Concentration)
Normal Adult Range: 32 - 36 %
Optimal Adult Reading: 34
Higher ranges are found in newborns and infants


R.B.C. (Red Blood Cell Count)
Normal Adult Female Range: 3.9 - 5.2 mill/mcl
Optimal Adult Female Reading: 4.55
Normal Adult Male Range: 4.2 - 5.6 mill/mcl
Optimal Adult Male Reading: 4.9
Lower ranges are found in Children, newborns and infants


W.B.C. (White Blood Cell Count)
Normal Adult Range: 3.8 - 10.8 thous/mcl
Optimal Adult Reading: 7.3
Higher ranges are found in children, newborns and infants.


PLATELET COUNT
Normal Adult Range: 130 - 400 thous/mcl
Optimal Adult Reading: 265
Higher ranges are found in children, newborns and infants


NEUTROPHILS and NEUTROPHIL COUNT - this is the main defender of the body against infection and antigens. High levels may indicate an active infection.
Normal Adult Range: 48 - 73 %
Optimal Adult Reading: 60.5
Normal Children's Range: 30 - 60 %
Optimal Children's Reading: 45


LYMPHOCYTES and LYMPHOCYTE COUNT - Elevated levels may indicate an active viral infections such as measles, rubella, chickenpox, or infectious mononucleosis.
Normal Adult Range: 18 - 48 %
Optimal Adult Reading: 33
Normal Children's Range: 25 - 50 %
Optimal Children's Reading: 37.5

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