5/21/11

Is Leukemia in any way genetic or inherited? I have had grandfather's from both sides get it and one uncle die?


Is Leukemia in any way genetic or inherited? I have had grandfather's from both sides get it and one uncle die?

- J.S.
It may be genetic but less than 10% of all cancer cases are genetically linked. Leukemia may sometimes but but is not always a genetic disorder. But, in some cases, it has been observed that some genetic mutations correlate with leukemia. I don't know a whole lot about the chronic leukemias but since my son is fighting AML leukemia, I have read up on it.

Some genetic mutations that have been seen to be favourable for AML patients include:
- Translocation between chromosomes 8 and 21 (seen in patients with M2)
- Inversion of chromosome 16 (seen in patients with M4)
- Translocation between chromosomes 15 and 17 (seen in patients with M3)

Some genetic mutations that have been seen to be unfavourable for AML patients include:
- Deletion (loss) of part of chromosome 5 or 7 (no specific AML type)
- Translocation between chromosomes 9 and 11 (seen in patients with M5)
- Extra chromosome 8 (no specific AML type)

What do you think? Answer below! Leukemia Problems Remedies | FIGHT CANCER INFO
Leukemia — Comprehensive overview covers symptoms, causes, risk factors, treatment of this blood-related cancer.



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